Probing bacterial cell wall growth by tracing wall-anchored protein complexes

Regulation of bacterial cell wall growth.

During growth and propagation, a bacterial cell enlarges and subsequently divides its peptidoglycan (PG) sacculus, a continuous mesh-like layer that encases the cell membrane to confer mechanical strength and morphological robustness. The mechanism of sacculus growth, how it is regulated and how it is coordinated with other cellular processes is poorly understood. In this article, we will discu...

Comparative Study of Anchored Wall Performance with Two Facing Designs

The present study compared the performance of soldier pile and concrete bearing pad anchored wall facings. Using Abaqus finite element software, two case studies have been precisely represented for the facing designs and effects of the parameters of soil type, spacing of anchors and facings, surcharge and facing sizes were investigated. The analysis results indicate that the soldier pile method...

Bacterial cell wall composition and the influence of antibiotics by cell-wall and whole-cell NMR.

The ability to characterize bacterial cell-wall composition and structure is crucial to understanding the function of the bacterial cell wall, determining drug modes of action and developing new-generation therapeutics. Solid-state NMR has emerged as a powerful tool to quantify chemical composition and to map cell-wall architecture in bacteria and plants, even in the context of unperturbed inta...

Bacterial Cell Wall-induced Immunosuppression

Asingle intraperitoneal injection of bacterial cell walls derived from groupA streptococci (SCW)' into susceptible rats results in the development of acute and chronic erosive polyarthritis (1, 2) . The pathology of the lesion leading to joint destruction has been shown to be aT cell-dependent, cell-mediated response to the deposition of the group A streptococcal peptidoglycan-polysaccharide po...

SpeB modulates fibronectin-dependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein